3 ch (3C) Description: Selected Topics in Medicinal Chemistry. Prerequisite: CHEM3421.
Ghislain Deslongchamps
Office: Toole 237
Phone: 453-4795
ghislain@unb.ca
http://taxane.chem.unb.caDavid MaGee
dmagee@unb.ca
Larry Calhoun
calhoun@unb.ca
Sept. 10 - Dec. 3, 2008
Lectures: W, 2:30- 4:50, Toole 303
Prerequisite: CHEM 3421
Point your browser to http://learning.unb.ca and use your UNB PIN to login. Note: only students registered for CHEM 4513 have login privileges.
There are two parts to this course. The first part involves the preparation and presentation of a seminar (PowerPoint/Keynote) on a single paper from the recent medicinal chemistry research literature. The second part involves the creation of a wiki chapter on an important topic in current medicinal chemistry, followed by a presentation of the wiki in seminar format.
- Students will form teams of 3 for the duration of the term. Team assignments must be emailed to ghislain@unb.ca by Friday Sept. 12. Students who have not submitted team information by the deadline will be assigned one by the seminar coordinators. The final team assignment will be posted on Blackboard by Monday Sept. 15.
- Seminars must be of a minimum duration of 30 minutes, followed by a 10 minute question period.
- Seminars must focus on a single research paper in the area of medicinal chemistry published in 2008 and must emphasize medicinal chemistry aspects (rather than molecular biology/genetics/immunology, etc).
- Selected papers (pdf copies) must be emailed to ghislain@unb.ca for approval at least 14 days prior to the scheduled seminar date. Once approved, the pdf copies will be made available to the class on Blackboard.
- Here is a partial list of appropriate journals for seminar preparation:
Angewandte Chemie, International Edition English
Biochemistry
Bioorganic and Medicinal Chemistry Letters
Chemistry: A European Journal
Chemistry & Biology
European Journal of Medicinal Chemistry
Journal of Biological Chemistry
Journal of Chemical Information and Modeling
Journal of Computational Chemistry
Journal of Computer-Aided Molecular Design
Journal of The American Chemical Society
Journal of Medicinal Chemistry
Journal of Organic Chemistry
Nature
New Journal of Chemistry
Proceedings of the National Academy of Science
Proteins
Science
Trends in Biochemical Sciences
- Seminars will be presented during the period of Oct. 8 - Oct. 29. The presentation order will be determined at random and will be posted on Blackboard by Monday Sept. 17, 9:00 am.
- Course coordinators will assign an individual seminar grade for each member of the student team based on Content (40%), Presentation (40%) and Handling of Questions (20%) and use this to assign a letter grade for each seminar. The letter grade, as well as feedback from the course coordinators will be relayed to the presenters within one week of their presentation.
- Questions will arise from students in the class. Each week, student participation in the question period will be assessed by the course coordinators (number and quality of questions). All students are strongly encouraged to read the paper prior to the seminar date. Course coordinators may ask supplemental questions at the end of the student question period if time allows.
- A wiki is a web-based collaborative authoring tool for creating/editing the content of a website. It provides an intuitive way of creating web pages and a system for monitoring individual changes that occurs over time (and who made the changes).
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Students will participate in constructing a wiki on medicinal chemistry topics in a fashion similar to the Wikipedia project, a web-based encyclopedia written and edited by a community of contributors. Student teams (same as for seminar) will select an important topic related to medicinal chemistry and develop a wiki-ready chapter complete with text, media, and bibliography. All wiki materials will be created, linked, indexed, and edited/corrected by the class participants, and made accessible through Blackboard.
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The wiki chapter must focus on a general topic rather than a single paper. Students must have a topic approved by Dr. Deslongchamps at least 21 days prior to the scheduled wiki presentation date and may begin contributing to the wiki as soon as their topic has been approved. Once approved, wiki topics will be posted on Blackboard and on the wiki itself.
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All wiki contributions must be completed by their respective presentation date, after which the wiki will be frozen (i.e. read-only). During the period of Nov. 12 - Dec. 3, student teams will do a "live" presentation of their wiki of a 30 minute duration, followed by a 10 minute question period from class participants. The presentation may be assisted by PowerPoint if a team deems the projection of the wiki itself inadequate for public presentation (i.e. small font size, information density, etc.).
- The presentation order will be the same as for the seminar and will be posted on Blackboard by Monday Sept. 15.
- Course coordinators will grade wiki presentations based on Content (40%), Presentation (40%) and Handling of Questions (20%) and use this to assign a letter grade.
- Questions will arise from students in the class. As in the first round of seminars, the question period will be assessed by the course coordinators (number and quality of questions). Class participants are strongly encouraged to read the wiki chapter prior to the presentations. Course coordinators may ask supplemental questions at the end of the student question period if time allows.
- For each student team, the seminar coordinator(s) will grade the wiki chapter itself based on overall quality, layout, and readability.
Sept. 10: Course outline - Presentation skills - (GD)
Sept. 12: deadline for submitting team assignments
Sept. 15: posting of final team assignment and seminar/wiki presentation schedule on Blackboard
Sept. 17: no class
Sept. 24: no class
Oct. 1: no class
Oct. 8: Seminar presentations - teams 1, 2, 3
Oct. 15: Seminar presentations - teams 4, 5, 6
Oct. 22: Seminar presentations - teams 7, 8, 9
Oct. 29: Seminar presentations - teams 10, 11, 12
Nov. 5: no class
Nov. 12: Wiki presentations - teams 1, 2, 3
Nov. 19: Wiki presentations - teams 4, 5, 6
Nov. 26: Wiki presentations - teams 7, 8, 9
Dec. 3: Wiki presentations - teams 10, 11, 12
| Seminar: | ||
| Presentation* | 30% | |
| Wiki: | ||
| Wiki chapter** | 20% | |
| Wiki presentation* | 30% | |
| Class participation*** | 20% | |
| TOTAL**** | 100% |
* The seminar coordinator(s) will assign an individual grade for each member of the student team based on the following criteria:
- content (depth of material, extent of coverage, correctness of information, length of presentation): 40%
- presentation (comprehensibility, organization, visuals, overall verbal communication, ): 40%
- handling of questions: 20%** The seminar coordinator(s) will assign a grade for the student team based on overall layout, readability and effectiveness of the wiki chapter.
*** Based on question periods following presentations.
**** Attendance is mandatory. 1 unjustified absence: -10/100 points; 2 unjustified absences: -20/100 points
| A+ A A- B+ B B- C+ C D F |
90 % 85 % 80 % 74 % 68 % 62 % 56 % 50 % 40 % <40 % |
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